Atosiban acetate
CAS No. 914453-95-5
Atosiban acetate ( RW22164;RWJ22164 )
Catalog No. M19935 CAS No. 914453-95-5
Atosiban is an inhibitor of the hormones oxytocin and vasopressin. It is used as an intravenous medication as a labour repressant (tocolytic) to halt premature labor. Atosiban inhibits the oxytocin-mediated release of inositol trisphosphate from the myometrial cell membrane.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 60 | Get Quote |
|
10MG | 105 | Get Quote |
|
25MG | 160 | Get Quote |
|
50MG | 195 | Get Quote |
|
100MG | 254 | Get Quote |
|
500MG | 626 | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameAtosiban acetate
-
NoteResearch use only not for human use.
-
Brief DescriptionAtosiban is an inhibitor of the hormones oxytocin and vasopressin. It is used as an intravenous medication as a labour repressant (tocolytic) to halt premature labor. Atosiban inhibits the oxytocin-mediated release of inositol trisphosphate from the myometrial cell membrane.
-
DescriptionAtosiban is an inhibitor of the hormones oxytocin and vasopressin. It is used as an intravenous medication as a labour repressant (tocolytic) to halt premature labor. Atosiban inhibits the oxytocin-mediated release of inositol trisphosphate from the myometrial cell membrane. As a result there is reduced release of intracellular stored calcium from the sarcoplasmic reticulum of myometrial cells and reduced influx of Ca2+ from the extracellular space through voltage gated channels. In addition atosiban suppresses oxytocin-mediated release of PGE and PGF from the decidua. In human pre-term labor atosiban at the recommended dosage antagonizes uterine contractions and induces uterine quiescence. The onset of uterus relaxation following atosiban is rapid uterine contractions being significantly reduced within 10 minutes to achieve stable uterine quiescence.
-
SynonymsRW22164;RWJ22164
-
PathwayOthers
-
TargetOther Targets
-
RecptorOthers
-
Research AreaOthers
-
IndicationPreterm labour
Chemical Information
-
CAS Number914453-95-5
-
Formula Weight1054.24
-
Molecular FormulaC45H71N11O14S2
-
Purity>98% (HPLC)
-
SolubilityDMSO:10 mM
-
SMILESCC(O)=O.CCOc1ccc(C[C@H]2NC(=O)CCSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](NC2=O)[C@@H](C)CC)[C@@H](C)O)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCN)C(=O)NCC(N)=O)cc1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Akerlund M et al. The effect on the human uterus of two newly developed competitive inhibitors of oxytocin and vasopressin. Acta Obstet Gynecol Scand. 1985;64(6):499-504.
molnova catalog
related products
-
Platelet Factor 4 (5...
Platelet Factor 4 (58-70), human is a polypeptide based on the 58-70 amino acid sequence of Platelet Factor 4 (pf-4) residues.
-
m-PEG16-alcohol
m-PEG16-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
-
Arnicolide C
Arnicolide C exhibits significant antiallergy activity.